New Delhi: A new variant of COVID-19, NB.1.8.1, has been found among travelers at multiple U.S. airports and most recently in India, prompting new concerns as worldwide cases are starting to increase again. The subvariant, which is derived from the Omicron lineage JN.1, has a few significant mutations within its spike protein that could potentially facilitate easier transmission. Though it’s presently listed by the World Health Organization as a ‘variant under monitoring,’ no evidence to date suggests that it’s leading to more serious sickness.
Is NB.1.8.1 the same as previous Omicron sub-variants?
In an interaction with News9Live, Dr Avala Ravi Charan, MBBS, DTCD, DNB ( NIMS ) Gold Medalist, Consultant Interventional Pulmonologist, Apollo Hospitals, Visakhapatnam, spoke about the new variant and the many complications that may arise.
All reported cases of NB.1.8.1 so far have presented symptoms closely akin to those of previous Omicron variants—mild sore throat, mild fever, tiredness, runny nose, and dry cough. These usually present themselves in the first couple of days of infection and tend to be self-managed at home. Nevertheless, like previous variants, older adults, those with pre-existing medical conditions, and those with compromised immune systems should continue to exercise caution since they could experience a greater risk of complications.
India has so far confirmed a case of this variant in Tamil Nadu and five in Andhra Pradesh, and other fresh variants, such as LF.7, have been found in Gujarat. Experts are not sounding the alarm yet, however, they do emphasise the need to remain vigilant. That entails still keeping masks on in crowded areas, washing your hands, keeping booster shots up to date, and getting tested early if you’re not feeling well. There are also about five cases in Andhra Pradesh of this variant. The development of NB.1.8.1 is a timely reminder that COVID-19 hasn’t gone away—it’s mutating. Being informed and vigilant is our best protection.
Are the new COVID-19 variants transmissible?
Dr. Sameer Bhati, Public Health Expert, spoke about the transmissibility and importance of the vaccine.
NB.1.8.1, a sublineage of the JN.1 Omicron subvariant, is showing high transmissibility and strong immune escape capabilities, which means even vaccinated individuals or those previously infected may get reinfected. It is not listed as a Variant of Concern or Interest by WHO so far, but close monitoring has been advisable due to its potential spread. It has been observed to cause only mild symptoms affecting the upper respiratory tract, such as sore throat, low-grade fever, body aches, and fatigue; quite a few remain unaware as they are asymptomatic.
With hybrid immunity imparted through vaccines and previous infection, there is a strong defence provided by memory B and T cells to churn out antibodies whenever reinfection occurs. High-risk individuals, such as the elderly or immunocompromised, however, should remain cautious, as even mild strains can cause complications. Sampling for testing is important with an RT-PCR test for early detection. Should the test return positive, isolation, monitoring of vitals, and avoidance of self-medication must be observed. Early intervention will curtail the transmission of the infection in society. We need to remain vigilant and follow guidelines, ensuring everything is safe without creating hysteria, especially at times of surging global incidences.
What are the symptoms of the NB.1.8.1 COVID variant?
Dr Nidhin Mohan, Consultant Internal Medicine, Narayana Health City, Bengaluru, listed the symptoms of the infection.
The recent detection of the NB.1.8.1 COVID variant at US airports highlights the continued evolution of the SARS-CoV-2 virus amid a global uptick in cases. While comprehensive data on this subvariant is still emerging, early reports suggest it shares similarities with other Omicron offshoots—exhibiting high transmissibility but, so far, not indicating increased severity.
Common symptoms continue to include mild fever, fatigue, sore throat, and nasal congestion, though we urge caution as symptom profiles may evolve. Importantly, vulnerable populations—such as the elderly and immunocompromised—should remain vigilant, especially in the context of international travel and large gatherings. In response, updated COVID care guidelines emphasize early diagnosis, home isolation for mild cases, and hospital referral for patients showing respiratory distress, low oxygen saturation, or comorbidities. Continued vaccination, including booster doses, remains our strongest line of defense.
We also wish to clarify the concept of lower-grade hyperthermia—an elevation in body temperature typically ranging between 99°F and 100.9°F. Unlike high-grade fever, it often indicates an early immune response rather than a severe infection. In COVID cases, such low-grade fevers may be one of the first signs and can persist longer in mild infections. It’s important not to dismiss these symptoms, especially when accompanied by fatigue or a dry cough.
NB.1.8.1 in India
Furthermore, Dr. Rita Bakshi, Senior Gynecologist and Co-founder of RISAA IVF, spoke about the scope of this new variant in India – should you be worried?
A new COVID-19 variant called NB.1.8.1 has been found in people who are traveling through big airports in the United States. According to the CDC, this variant can be one reason why COVID cases are rising again in China and some other countries in Asia. This shows that the virus is still changing, and new types can appear anytime.
In India, this variant was found in April through wastewater testing. The World Health Organization (WHO) and CSIR-NEERI found one case in Tamil Nadu. Additionally, experts have put this variant in the “Variant Under Monitoring” list. This means that it is not dangerous yet, but it still needs attention. This variant has some changes (called mutations) in its structure, including A435S, V445H, and T478I. These may help it to spread faster or avoid some immunity. However, for now, WHO says the risk from this variant is low around the world.
The symptoms of NB.1.8.1 are almost the same as the earlier COVID variants. These include sore throat, cough, tiredness, fever, and blocked nose. Some people also feel nausea, headache, stomach problems, and extreme weakness. In some cases, people had a low-grade fever that stayed for a few days. However, this variant does not seem very dangerous right now. But it might spread more or lower the chances of how good vaccines work because of its changes. That’s why doctors are watching everything closely. Additionally, doctors are suggesting wearing masks in crowded places, washing hands, getting tested if sick, and keeping your vaccines up to date to stay safe from this variant.
A new COVID-19 variant called NB.1.8.1 has been found in people who are traveling through big airports in the United States. According to the CDC, this variant can be one reason why COVID cases are rising again in China and some other countries in Asia. This shows that the virus is still changing, and new types can appear anytime. Health News Health News: Latest News from Health Care, Mental Health, Weight Loss, Disease, Nutrition, Healthcare
